Longevity

How I evaluate drugs for longevity and long term health

How I evaluate drugs for longevity and long term health

A practical framework for deciding which habits and drugs make sense for longevity, using risk benefit analysis, biomarkers, and caution around metformin.

Biological age tests: what they measure and how to use them

Biological age tests: what they measure and how to use them

Biological age tests can motivate change, but results vary and often reflect the past. Learn how to interpret them and prioritize proven markers.

Medical AI and risk testing for a longer, better life

Medical AI and risk testing for a longer, better life

Medical AI is speeding discovery and improving clinical work. Risk tests are becoming more accessible. Use them to motivate habits, not chase biohacks.

Exercise for longevity: clear strength and VO2 targets

Exercise for longevity: clear strength and VO2 targets

Turn exercise into a measurable prescription: minutes, intensity, strength progress, and VO2. Use benchmarks to adjust the plan when you are not improving.

Leucine and protein: how to keep your muscle after 40

Leucine and protein: how to keep your muscle after 40

Leucine can support strength and muscle function with age. Practical dosing with meals, what to track, and when it is unlikely to add value.

Blood factors and exercise signals that help the brain

Blood factors and exercise signals that help the brain

Animal studies suggest young blood factors and post exercise signals can reduce brain inflammation and improve memory. What it means and what it does not.

Strength training to slow sarcopenia and age better

Strength training to slow sarcopenia and age better

Strength is not just aesthetics. A simple resistance plan plus enough protein improves function, preserves muscle, and reduces frailty risk as you age.

Peptides and biological age: how to avoid hype in longevity

Peptides and biological age: how to avoid hype in longevity

Learn how to interpret biological age claims and demand evidence when peptides, trendy therapies, and misleading photos are used to sell rejuvenation.

Discover longevity drugs beyond rapamycin at scale

Discover longevity drugs beyond rapamycin at scale

Why large scale molecule discovery can unlock longevity therapeutics and radiation resilience, and how to evaluate claims with auditable evidence.

Five markers that best predict long term longevity

Five markers that best predict long term longevity

Blood pressure, apoB, VO2 max, relative strength, and body composition: five practical metrics to guide habits and health decisions for the long run.

Athlete longevity: a simple routine to stay strong

Athlete longevity: a simple routine to stay strong

Sleep, hydration, training, and nutrition without confusion. Lessons to feel strong now and still have energy at 80.

Plasma exchange and biological age: promises and limits

Plasma exchange and biological age: promises and limits

Therapeutic plasma exchange is being explored for aging biomarkers. Learn what it is, what is known, and which questions to ask before believing claims.

How to evaluate longevity drugs without falling for hype

How to evaluate longevity drugs without falling for hype

Metformin, rapamycin, and resveratrol sound promising, but data decides. A practical guide to reading trials, spotting bias, and knowing what not to do.

GLP-1 and longevity: real benefits and clinical limits

GLP-1 and longevity: real benefits and clinical limits

A practical review of GLP-1 use in obesity and cardiometabolic health, including benefits, limits, and risk management.

Protein, oils, and guidelines: what current evidence shows

Protein, oils, and guidelines: what current evidence shows

A critical review of plant protein, dietary fats, and policy decisions that shape diet quality and cardiometabolic outcomes.

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