Triglycerides and HDL: a better marker of heart risk

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For years cholesterol has been discussed as if one number could predict heart risk. Yet many people have a heart attack with LDL in the normal range. This does not mean cholesterol does not matter. It means metabolic context often matters as much or more. Triglycerides and HDL, and the relationship between them, frequently reflect insulin resistance and particle quality, which are tied to real world risk.

Why LDL does not tell the whole story

LDL is an indirect measure of lipoprotein traffic, not a complete picture. Two people can share the same LDL value and have very different risk if one has higher inflammation, poor glucose control, or small dense particles. That is why focusing only on a numeric target can miss the primary issue.

A large share of people who experience a cardiac event show LDL below common thresholds. That reality pushes you to consider additional markers.

Triglycerides and HDL as a window into metabolism

Triglycerides often rise when the liver handles excess energy, especially from added sugars and refined starches. HDL tends to drop in insulin resistant states. When you see high triglycerides and low HDL, the pattern suggests a more atherogenic profile.

That profile is often associated with smaller denser LDL particles that oxidize more easily and can penetrate the arterial wall more readily. It is not only how much cholesterol you carry, it is how you carry it.

The triglycerides to HDL ratio, how to use it

Your clinician can calculate it from a standard lipid panel. It does not replace medical evaluation, but it provides a useful clue.

  • A higher ratio often travels with insulin resistance.
  • A lower ratio often reflects better carbohydrate handling and a healthier lipid profile.

Do not panic about one value. Use it to decide which habits to prioritize and what follow up makes sense.

Habits that worsen triglycerides and HDL

  • Sugary drinks and frequent desserts.
  • Excess bread, pasta, and refined snacks.
  • Regular alcohol, especially in large amounts.
  • Low activity.
  • Short sleep.

When these combine, visceral fat rises and insulin sensitivity worsens.

A practical strategy to improve your lipid profile

For most people, improvements come from repeatable choices.

Nutrition

  1. Cut added sugar and highly refined starch.
  2. Increase protein and vegetables at each meal.
  3. Include quality fats such as olive oil, nuts, and fish.
  4. Add fiber from legumes, vegetables, and fruit.

Activity

  • Do strength training two or three days per week.
  • Walk daily. Consistency matters more than occasional intensity.

Sleep and stress

Short sleep increases appetite and worsens insulin sensitivity. Keep a stable schedule and protect your night routine.

When medication enters the discussion

Statins and other therapies can be appropriate for certain risk profiles, especially with prior events or specific genetics. But the best plan depends on your history, full labs, and tolerance. Talk with your clinician about targets, benefits, and possible side effects.

What to request if you want a more precise picture

If you want deeper risk insight, your clinician may consider additional markers.

  • Non HDL cholesterol as a summary of atherogenic cholesterol.
  • ApoB to estimate particle number.
  • Lipoprotein(a) when there is family history of early events.
  • High sensitivity C reactive protein when inflammation is part of the evaluation.

Not everyone needs all of these. Use them when results change decisions and when you can act on them.

A simple three month habit plan

Triglycerides and HDL often respond quickly to consistent changes.

  1. Eat a protein focused breakfast, such as plain yogurt with fruit or eggs with vegetables.
  2. Pick one main carbohydrate per meal, ideally whole grain or legumes.
  3. Walk ten minutes after two meals per day.
  4. Keep alcohol low and avoid drinking on many consecutive days.
  5. Repeat labs in three months with stable habits and a similar blood draw time.

This type of plan improves insulin sensitivity and can improve lipid patterns alongside it.

Fine tuning that often matters

Once the basics are in place, two levers often stand out.

First, review alcohol. Even moderate intake can raise triglycerides in some people. Second, review your eating window. Very late dinners and late night snacking can worsen glucose control and sleep.

A useful approach is keeping two main meals built around protein and fiber while reducing snacks. It is not a rigid diet, it is a way to reduce repeated sugar and calorie exposures that push triglycerides up.

If you train, place carbohydrates closer to training and reduce refined carbs during low activity parts of the day.

Also track waist size and blood pressure over time. These often improve as insulin resistance improves and can give you an early signal that your plan is working.

Conclusion

To assess heart risk, look beyond LDL. Triglycerides, HDL, and their ratio often reflect metabolic health and insulin resistance. When you act on diet, activity, sleep, and alcohol, you can improve markers and reduce true risk over time.

Knowledge offered by Dr. Mark Hyman

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