Medical AI and risk testing for a longer, better life
Original video 55 min4 min read
Longevity is full of noise. Between biohacking, anti aging promises, and constant trends, it is easy to lose track of what actually improves health and quality of life. A more useful view is evidence based: understand risk, apply lifestyle fundamentals, and use technology to make prevention practical.
Two forces are colliding. On one side, biomedical science is moving fast with real breakthroughs. On the other, there is real strain from budget cuts, misinformation, and decisions that can slow research and access. In the middle sits a tool that changes the pace of progress: artificial intelligence.
Why science matters if you want to live longer
Public health and biomedical research are not abstract. They are how we discover treatments, quantify risk, and bring new tools into the clinic. When budgets are cut or decisions become politicized, the impact is not only academic: timelines slip, talent leaves, and narratives without data gain ground.
In longevity, this matters even more because many useful interventions are preventive and long term. The return on investment is measured in decades, which makes continuity critical.
Medical AI: from research to the clinic
AI is not only about chatbots. There are clear areas where it can create real value.
Drug discovery
AI is being used to accelerate the search for new drugs. A commonly cited example is a drug candidate for idiopathic pulmonary fibrosis that advanced through clinical testing after being discovered with AI support. The point is not magic. It is speed in exploration and iteration.
More efficient clinical work
AI is also changing day to day care. Turning patient conversations into high quality clinical notes can free up hours per day for clinicians. That time can go back to what matters most: the patient clinician relationship. The same systems can assist with administrative work such as ordering tests, coding, prescriptions, scheduling follow ups, and prior authorizations, reducing friction.
The quiet revolution in risk testing
While headlines focus on controversies, a quieter revolution is happening: tests that estimate risk more precisely and, in some cases, more affordably than many people expect. The challenge is that accessibility has not automatically turned into routine use, because awareness is low and clinicians cannot track every advance at the same speed.
Concepts that sound distant already exist:
- Polygenic risk scores for multiple conditions.
- Genome sequencing.
- Organ clocks or metrics that estimate biological aging by system.
- Advancing biomarkers, including some proteins associated with neurological risk.
A major barrier is cultural. Many clinicians are not up to date because clinical load is heavy and the innovation cycle is hard to follow. There is also a knowledge gap in the wider medical community: even good doctors may not mention these options because they have not had time to integrate them into standard practice. AI may help close that gap over time, but only if it is paired with clear guidelines on when a test is useful.
How to use tests without falling into biohacking
The right question is not which test is trending. It is what decision changes with the result.
At best, risk testing activates behavior. Many people know they should improve nutrition, exercise, and sleep, but they do not act until they learn that their personal risk for a specific condition is higher than they assumed. Knowing risk at a specific time point can be the trigger that turns vague intentions into consistent action.
There are limits.
- If your lifestyle fundamentals are already strong, you may not need advanced tests.
- If a test does not lead to a clear action, it can create anxiety without benefit.
- Privacy and data use should be part of the decision.
A practical plan to decide what to do
- Start with fundamentals: nutrition, exercise, and sleep.
- Add layers: social connection and time in nature also matter.
- Apply moderation. You do not need daily perfection, but you do need consistency.
- If you struggle to activate habits, choose one test that has a clear action tied to the result.
The point is not to test everything. The point is to use one good signal to support behavior change, then measure progress through habits and outcomes that you can sustain.
- Avoid collecting tests. Pick one or two priorities and review results with a professional.
- Repeat at a sensible cadence. Prevention is a process, not a single event.
Conclusion
Medical AI is accelerating discovery and improving clinical efficiency. At the same time, risk tests are becoming more accessible, even though most people and many clinicians still do not use them routinely. The smartest approach is to use technology to support decisions and habits without chasing hype. Living longer and better still depends on the basics, but better information can help personalize the path.
Knowledge offered by Dr. Eric Topol