Creatine: realistic dosing and evidence based benefits
Original video 59 min4 min read
Creatine has moved from a classic training supplement to a mainstream trend. Along the way, exaggerated promises showed up: that it feels like a stimulant, that it replaces caffeine, or that it reverses aging. If you want to make good decisions, separate what creatine reliably does, what only shows up in specific contexts, and what is pure marketing.
The practical conclusion is fairly simple. Creatine has strong evidence for supporting body composition when combined with resistance training. It may have modest short term cognitive effects under stress, such as sleep deprivation. And there is no good evidence based reason to take chronic megadoses.
What creatine actually does
Creatine helps maintain and refill phosphocreatine stores, a fast energy system for short, intense efforts. Think of it as a backup battery that can support hard reps or short sprints. This does not mean it transforms you on its own. The benefit shows up mainly when you lift and creatine helps you do a bit more useful work over time.
That is the correct frame: creatine plus resistance training. If you do not train, the expected impact on body composition is small.
Realistic dosing: less hype, more useful
For most people, the most reasonable standard dose is 5 g per day, every day. You do not need complicated calculations. Consistency matters because the goal is to keep stores high.
Online, 20 g per day has become popular. The issue is that evidence for 20 g outperforming 5 g per day in a sustained way is very limited. You might experiment in specific situations, but it is not a smart default.
If you want to try 20 g out of curiosity, treat it as a one time experiment, for example after a night of poor sleep. Notice how you feel, then return to your standard dose.
What you may notice when starting
Some people report a small early weight increase from water retention in muscle. That is not muscle built overnight. A better signal is performance over time, not daily scale fluctuations.
If you miss a day
Do not worry. Stores do not drop enough in a single day to matter. The priority is returning to your routine without turning it into an obsession.
Benefits outside the gym: modest and situational
There are interesting signals that creatine may help maintain short term cognitive function under stress, such as low sleep. That does not equal constant brain optimization. In healthy, well rested people, the expected effect is smaller.
It is also important to limit extrapolation. A good energy mechanism does not automatically translate into solving complex diseases. In chronic neurological conditions, enthusiasm is typically lower and evidence is not as compelling as it is for strength and performance.
When to take it and how
There are no good studies showing that taking creatine before training, after training, in the morning, or before bed produces meaningfully different results. Once your stores are saturated, timing matters less because you are maintaining a steady baseline.
A practical way to think about it is this: your body refills the backup battery whenever there is enough energy available. As long as you take 5 g per day consistently, you are supporting that refill process. So the best time is the time you can remember.
Attach it to a stable routine, such as mixing it into water during training or into your first drink of the day. If it feels better with food, take it with a meal.
Risks, side effects, and how to spot marketing
At normal doses, creatine is generally well tolerated. Still, some people notice digestive discomfort with high doses or when taking too much at once. At 20 g per day, beyond minor issues like stomach upset, there is a reasonable uncertainty: we have less long term population data on decades of chronic use at that dose.
Another red flag is treating the supplement as a hack or crutch. Creatine can be a sensible add on, but it only adds real value if the foundation is in place. Think in order: eat, move, sleep, connect. Then, if you want, creatine.
A checklist for using it well
- Lift regularly. Without that, do not expect large changes.
- Take 5 g per day consistently.
- Do not chase megadoses without a clear reason.
- Adjust if digestive discomfort shows up, such as splitting the dose.
- Evaluate outcomes with performance and adherence, not one day sensations.
Conclusion
Creatine belongs on the short list of supplements with strong evidence for supporting resistance training. It may also provide a modest cognitive benefit under stress, such as poor sleep, but it is not a superpower. Keep dosing simple at 5 g per day and keep the fundamentals strong to get the upside without the noise.
Knowledge offered by Dr. Matt Kaeberlein